Objective: To investigate the implementation of multidisciplinary collaboration led by enterostomal therapists (ET) for risk management of wound treatment and the effect.  
Methods: The data of all patients attending the Center of Wound Care of Xiangya Hospital from May 2013 to April 2017 were collected. The process of multidisciplinary collaboration led by ET for risk management of wound treatment was implemented in patients admitted since May 2015, which included risk assessment, risk analysis, risk identification, and risk decision, and in those regarded as important individuals due to obvious treatment and operative difficulties or potential medical disputes, a series of risk prevention and control measures were performed in partnership with multidisciplinary team. The number, constitution and source of patients as well as patients’ satisfaction rate, and incidence of adverse events were compared before and after implementation of the process.
Results: After implementation, the total number of admitted patients increased by 27.74%, the number of referrals from doctors increased by 54.76%, the number of patients with chronic wounds increased by 51.34%, and the number of ward consultations increased by 52.63% compared with those before implementation. The incidence of adverse events was significantly reduced (0.05% vs. 0.12%, P<0.05) and the patients’ satisfaction rate was significantly increased [(95.36±0.52) % vs. (90.34±0.45) %, P<0.05] after implementation comparted with those before implementation. 
Conclusion: Implementation of multidisciplinary collaboration led by ET for risk management of wound treatment can reduce the incidence of adverse events, increase the patients’ satisfaction rate and improve the wound treatment efficacy. So, it is recommended to be used in clinical practice.