Objective: To evaluate the early efficacy and safety of Angiojet mechanical thrombectomy in treatment of patients with postoperative deep venous thrombosis (DVT).   
Methods: The clinical data of 91 patients with acute DVT (central or mixed type) treated from September 2015 to January 2017 were retrospectively analyzed. Of the patients, 30 cases had postoperative DVT (observation group) and 61 cases had non-postoperative DVT (control group). The relevant clinical variables between the two groups were compared. 
Results: There were no significant differences in terms of preoperative data between the two groups of patients (all P>0.05). The stent implantation rate as well as the diameter and length of the stents showed no significant differences between the two groups (all P>0.05), but the average time for thrombolysis in control group was significantly longer than that in observation group (2.31 d vs.1.50 d, P<0.05). There were no serious complications such as major bleeding events and cardiovascular events or death occurred in either of the groups. Puncture site bleeding occurred in 6 cases and 4 cases and newly developed symptomatic pulmonary embolism occurred in 
2 cases and 1 case in control group and observation group respectively, and the differences showed no statistical significance (both P>0.05). The 1-year patency rate (control group: 88.52% vs. observation group: 90.00%), VRI score and Villalta score showed no statistical difference between the two groups (all P>0.05).
Conclusion: Using Angiojet mechanical thrombectomy in treatment of postoperative DVT is safe and effective.