Objective: To investigate the safety, feasibility and effectiveness of using enhanced recovery after surgery (ERAS) concept in precise laparoscopic hepatectomy for hepatic hemangioma.   
Methods: The clinical data of 96 patients undergoing precise laparoscopic hepatectomy for hepatic hemangioma from January 2014 to January 2019 were retrospectively analyzed. Of the patients, 40 cases received perioperative management directed by ERAS concept (ERAS group), and 56 cases underwent perioperative management with a conventional protocol (control group). The preoperative general characteristics, intraoperative variables, length of postoperative hospital stay, hospitalization costs, incidence of postoperative complications, liver function recovery patterns, and C-reactive protein (CRP) as well as other laboratory indicators were compared between the two groups.
Results: There were no statistical differences in any preoperative or intraoperative variables between the two groups (all P>0.05). In ERAS group, the length of postoperative stay was significantly shortened and the hospitalization cost was significantly reduced compared with control group (both P<0.05). As for the laboratory parameters, the CRP level on postoperative day 7 was significantly lower in ERAS group than that in control group (P<0.05), but all other parameters showed no significant differences between the two groups (all P>0.05). There were no statistical differences in incidence of each postoperative complication and readmission rates between the two groups (all P>0.05).  
Conclusion: In patients undergoing precise laparoscopic hepatectomy for hepatic hemangioma, using perioperative ERAS is safe and feasible, and it can reduce the length of hospital stay, the hospitalization cost and the surgical stress response, and accelerate the postoperative recovery of the patients.