At present, the outbreak of novel coronavirus pneumonia (NCP, WHO named as COVID-19) poses a serious threat to the lives and health of people in China. Under the background of the NCP epidemic, there many new challenges for surgeons who practice vascular surgery, such as how to handle the patients attending vascular surgery outpatient clinics, how to deal with the serious and critical patients requiring emergency vascular surgery, how to safely perform the vascular surgery procedures, and how to properly perform the postoperative management and follow-up of vascular surgery patients. Here, the authors based on the latest literature data and the prevention and control experience of the hospital where the authors work, address the above issues and also offer the personal suggestions, with the hope of serving as a lead-in to further discussions, and inspiring the vascular surgeons to think about how to conduct the vascular surgical diagnosis and treatment during the epidemic of NCP, so as to improve the clinical practice.