The epidemic situation of new coronavirus pneumonia (COVID-19) is currently still severe in our country. In the face of the epidemic, how to efficiently and properly carry out breast cancer treatment with implementing the standardized protocol as a premise is not only an extremely urgent medical problem, but also a social issue related to people’s livelihood. Here, the authors combined with the discussion of clinical cases, attempt to offer solutions to the problems in breast cancer treatment resulting from the special circumstances of COVID-19 epidemic, so as to provide ideas for breast cancer treatment during the period of COVID-19 outbreak.