Background and Aims: The occurrence of intravascular foreign bodies is relatively common in clinical practice, especially the intravascular foreign bodies caused by iatrogenic factors. With the increase of number of medical invasive procedures, the occurrence of iatrogenic intravascular foreign bodies is also increasing, which may lead to serious complications in patients. Therefore, the occurrence and development of intravascular foreign bodies as well as their diagnosis and treatment have also attracted attention and discussion from clinicians. Therefore, in order to optimize the diagnosis and treatment of such patients, and ensure the safety of the patients, this study conducted a comprehensive analysis and discussion based on the experience in diagnosis and treatment of intravascular foreign bodies in our department in the past two years, combined with the existing literature reports, so as to provide scientific theoretical basis and experience sharing for the diagnosis and treatment of similar cases in clinical practice. 
Methods: The clinical data of 4 patients with intravascular foreign bodies diagnosed and treated in our center in the past two years were collected, and the sources and characteristics of foreign bodies, surgical procedures and experience were retrospectively analyzed and sorted out. The existing domestic and foreign literature reports concerning such diseases were retrieved, and then were reviewed and summarized.
Results: All the 4 patients had iatrogenic intravascular foreign bodies, which in one case was caused by the guide wire detachment during placement of the peripherally inserted central catheter (PICC), in two cases were caused by the fracture of the PICC catheter, and in another case was causes by undesirable detachment of the coils in the abdominal aortic lumen during endovascular embolization for a penetrating aortic ulcer. None of the four patients had clinical manifestations related to foreign bodies. All the foreign bodies were successfully removed by using a single-bent catheter and a gooseneck snare under interventional approach, and the integrity of each foreign body was acceptable. All patients recovered well after operation without any foreign body and operation-related complications.
Conclusion: In clinical practice, the occurrence of intravascular foreign bodies cannot be completely avoided, especially those caused by iatrogenic factors, and effective preventive measures should be taken. For the already occurred intravascular foreign bodies, timely and effective treatment is extremely important to reduce the risk of serious complications caused by foreign bodies. As the preferred treatment for intravascular foreign bodies, endovascular interventional therapy has the unique advantages of high retrieval rate, low surgical risk and fewer complications, and its efficacy has also been proven. In addition, a variety of appropriate interventional instruments should be selected and experienced surgeons are necessary during endovascular interventional procedures.