肝脏常见病变磁共振显像的量化研究
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全显跃

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Quantitative study of magnetic resonance imaging in common hepatic lesions
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    目的:量化分析肝脏常见病变磁共振显像(MRI)T1值、T2值和磁共振弥散显像(DWI)表面扩散系数(ADC)的变化规律,以提高MRI诊断肝脏病变的准确性。方法:对100例肝脏常见病变行MRI及DWI,计算病变的T1、T2、ADC,以及肝细胞癌和肝转移瘤的瘤/肝ADC的比值。结果:病变的T1,T2、ADC的均值±标准差分别为:肝细胞癌为(843.92±167.75)ms,(73.90±14.21)ms和(0.99±0.26)×10-3mm2/s;肝转移瘤为(946.89±186.13)ms,(76.39±19.76)ms和(1.17±0.32)×10-3mm2/s;肝血管瘤为(1102.33±213.12)ms, (142.32±28.51)ms和(1.81±0.42)×10-3mm2/s;肝囊肿为(1516.32±617.84)ms,(247.33±112.52)ms和(3.11±0.38)×10-3mm2/s。瘤/肝ADC之比值:肝细胞癌为0.89±0.17,肝转移瘤为1.27±0.21,差异有显著性。结论:综合量化分析病变T2和ADC及瘤/肝ADC比值的变化规律,能准确地判断病变的性质,能使MRI对肝脏病变做出准确的诊断及鉴别诊断。

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    Objective:To evaluate the characteristics of MRI of common hepatic lesions by using measurement of T1,T2 and ADC on the MRI and DWI. Methods:MRI and DWI were obtained in 100 patients with common hepatic lesions, and T1,T2,ADCs and the ratios of the ADC of lesion/liver were estimated. Results:Average T1,T2 and ADCs of hepatic lesions were as follows: hepatocellular carcinoma, (843.92±167.75) ms , (73.90±14.21) ms and(0.99±0.26)×10-3mm2/s respectively; hepatic metastasis, (946.89±186.13) ms, (76.39±19.76) ms and(1.17±0.32)×10-3mm2/s respectively; hepatic cavernous hemangioma, (1102.33±213.12)ms, (142.32±28.51) ms and (1.81±0.42)×10-3mm2/s respectively; hepatic cyst, (1516.32±617.84)ms ,(247.33±112.52)ms and (3.11±0.38)×10-3mm2/s respectively. The ratio of the ADC of lesion/liver:hepatocellular carcinoma was 0.89±0.17, and significantly lower than the ratio of hepatic metastases(1.27±0.21, P<0.05). Conclusions:Quantative study of hepatic lesions using T2, ADC and the ratios of the ADCs of lesion/liver, can accurately distinguish the nature of the lesions, and MR1 can accurately diagnose and differentiate hepatic lesions.

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孙希杰,全显跃,许乙凯,梁文.肝脏常见病变磁共振显像的量化研究[J].中国普通外科杂志,2005,14(7):13-.
DOI:10.7659/j. issn.1005-6947.2005.07.013

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  • 在线发布日期: 2005-07-25