PET/CT与钼靶X线鉴别乳腺癌的比较研究
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孙靖中

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Evaluation of PET/CT imaging versus mammography in detecting breast cancer
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    摘要:

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    目的 评价PET/CT诊断乳腺癌的真实性,初步探讨其临床意义。
    方法 33例乳房肿块患者行钼靶X线和PET/CT检查,分别采用半定量和定性方法分析肿瘤病灶摄取氟脱氧葡萄糖(FDG)的程度和血流灌注情况,比较PET/CT和钼靶X线诊断乳腺癌的差异。
    结果 PET/CT诊断乳腺癌的敏感度、特异度和精确度分别为92.6%,100%和93.9%;钼靶X线的敏感度、特异度、精确度分别为81.5%,80.0%和78.8%;但两种方法的诊断效能无显著性差异(P>0.05)。
    结论 PET/CT诊断乳腺癌的敏感度、特异度和阳性预测值较高,并可提供更多方面的活体诊断信息,为治疗策略提供参考,弥补了钼靶X线之不足。

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    Abstract:Objective To evaluate the actual value of PET/CT in detecting breast cancer,and make a preliminary study of its clinical significance.
    Methods 33 patients with breast mass underwent PET/CT imaging and mammography.The degree of uptake of Fluorodeoxyglucose(FDG) and blood perfusion in the breast masses were respectively analyzed by semiquantitative and qualitative methods and the differences in findings of PET/CT and mammography in detecting breast cancer were compared. Results Breast cancer was diagnosed by PET/CT with sensitivity,specificity and accuracy rates of 92.6%,100% and 93.9%,respectively,and by mammography with rates of 81.5%,80% and 78.8%,respectively;in diagnostic ability,the two methods showed no significant difference(P>0.05). Conclusions In comparison with mammography,PET/CT has a higher degree of sensitivity and specificily in detecting breast cancer,and higher positive predictive value.PET/CT can provide more aspects of in vivo diagnostic information which may be useful in selecting therapeutic strategy and may supplement the inadequacies of mammography.

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邹海东 ,马榕 ,余之刚 ,刘庆伟 ,王成刚 ,李昕 ,孙靖中. PET/CT与钼靶X线鉴别乳腺癌的比较研究[J].中国普通外科杂志,2005,14(4):2-.
DOI:10.7659/j. issn.1005-6947.2005.04.001

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  • 收稿日期:2004-12-31
  • 最后修改日期:2005-03-25
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  • 在线发布日期: 2005-04-25