Abstract:Objective
To explore the status and perioperative management of liver transplantation in treatment of portal hypertension.
Methods Clinical data of 56 patients with portal hypertension who underwent orthotropic liver transplantation (OLT) from February 2000 to April 2004 were studied retrospectively.Incidence of complications,and inhospital mortality and survival rate were analyzed. Platelet count after OLT was measured and liver blood flow was monitored by Doppler.
Results Among the 56 OLT patients, 6 cases(10.7%) underwent simultaneous splenectomy. Incidence of complications was 40.3%,and inhospital mortality and 1-,2-,and 3- year survival rate after OLT were 12.5% and 87.46%,85.19% and 81.58% respectively. Platelet count reached a nadir at posttransplant day 3.
Conclusions OLT is an effective method for radical treatment of portal hypertension. Perioperative management is of vital importance for success of the operation and patient′s prognosis.