Abstract:Objective:To discuss the therapeutic effect of simple portal-azygous disconnection and modified Sugiura operation(MSO) in the treatment of portal hypertension.Methods:The operative safety, postoperative recovery, complications and follow-up results were compared between 30 cases of simple (simple group) and 34 cases of MSO. Results:The basic clinical informations were comparable between the two groups（P>0.05）.No intra-or post-operative severe complications nor mortality occurred in either group. There was no significant difference between the two groups in operative blood loss, postoperative recovery time and hospital stay days（all P>0.05）. The number of cases with disappearance of esophagcal varices was significantly higher in MSO group than in the simple venous disconnection group(P<0.05).Conclusions:The obliteration rate of esophageal varices is significantly better after the modified Sugiura operation than after the traditional disconnection operation. However,the long-term therapeutic effects are similar.