Abstract:Objective:To study the effect of partial portal vein arterialization on the liver of rats after partial hepatectomy. Methods:Forty eight SD rats underwent partial hepatectomy and were divided into nonarterialization group and arterialization group. Dynamic observation of serum ALT and AST,and changes of ATP,ADP and AMP in hepatic tissues were determined at 2h,6h and 12h after operation.EC values were also calculated, and hepatic tissues were obtained for pathologic examination. Results:（1）Compared to nonarterialization group, the serum AST and ALT of arterialization group showed no significant difference on the 2nd hour after the operation(P>0.05)，but，serum AST and ALT were significantly decreased on the 12th hour in arterialization group (P<0.01 and P<0.05). （2）Compared with nonarterialization group, the ATP content of liver tissue and EC value were significantly increased on the 2nd，6 th and 12th hour in arterialization group (P<0.01 and P<0.05). （3）Hepatic pathological changes were exacerbated progressively with the prolonged duration of ischemia in nonarterialization group, while the injury of hepatic cells in arterialization group was mild. Conclusions:The partial arterialization of portal vein can lessen the damage of the liver after partial hepatectomy and transection of hepatic artery, and can improved the energy metabolism of the hepatic cells.