Abstract:Objective ：To explore the diagnosis and surgical treatment of pancreatic duct stones.Methods ：The clinical data of 24 cases of pancreatic duct stones who underwent operation from 1985 to 2005 were analyzed retrospectively. Results ：The diagnosis of all cases was confirmed by imaging examinations such as B ultrasonography, abdominal X-ray film, CT， endoscopic retrograde cholangiopancreatography or magnetic resonance cholangiopancreatography . The operative methods were pancreatolithotomy with Roux-en-Y side-to-side pancreaticojejunostomy in 19 cases, distal pancreatectomy with pancreatojejunostomy in 4 cases and pancreatoduodenectomy in 1 case. No operative complication was found. Tweenty-four cases were followed for 2 months to 4 years after operation.Among 23 cases with upper abdominal pain before operation, the abdominal pain disappeared in 19 cases and was alleviated in 4 cases postoperatively. Among 8 cases with diabetes mellitus before operation, blood glucose returned to normal in 4 cases postoperatively. Among 5 cases with steatorrhea before operation, the steatorrhea disappeared in 2 cases and was alleviated in 1 case postoperatively. Conclusions ：Imaging examinations are the main methods for diagnosis of pancreatic duct stones. The main operative method is pancreatolithotomy with Roux-en-y side-to-side pancreaticojejunostomy.