Abstract:Objective：To study the value of modified splenopneumopexy in the treatment of Budd-Chiari syndrome（B-CS）. Methods：The clinical data of 126 patients with BCS treated by modified splenopneumopexy were analysed retrospectively. Results：In this series, the postoperative complication rate was 7.94%（112/126）, the perioperative mortality rate was 1.60%(2/126); and 86 cases were followed up for 9 months to 18 years, the mean time was （7.8±1.2）years, the effective rate was 83.7%（72/86）. Among them, 22 patients followed up by color Doppler ultrasound, and 16 patients by percutaneous splenoportography(1 month~6 years after operation), which showed the collateral circulation of various diameters and numbers between the spleen and lung was formed. In 8 cases the operation was ineffective or B-CS recurred. Six cases died, two of them died of hepatoencephalopathy 2 and 3 years after operation respectively, two of upper digestive tract rebleeding, and 2 of hepatocellularcarcinoma. Conclusions：Splenopneumopexy can decrease portal vein pressure, relieve hypersplenism and ascites, and control(or prevent) upper digestive tract bleeding. Splenopneumopexy is a valuable and worthy operation for B-CS, and can be widespread application.