Abstract:Abstract:Objective：To study the extrahepatic hemodynamic changes in portal system after DSRS+SPD and after DSRS+SPD+Disconnection in dogs. Methods：The FPP, POPP and MAP levels before operation, after DSRS+SPD and DSRS+SPD disconnection operation were measured; and the portal-system shunt(PSS) was calculated postoperatively. Results：After DSRS+SPD, FPP decreased（0.07±2.41）mmHg(P>0.05),POPP decreased(19.10±10.45)mmHg(P<0.01), MAP decreased (31.35±22.18)mmHg (P<0.01),PSS increased (4.53±4.09)% (P<0.01). After DSRS+SPD+Disconnection,FPP decreased (1.82±1.38)mmHg (P>0.05),POPP increased (11.14±8.85)mmHg (P<0.01), MAP decreased(9.83±7.59)mmHg (P>0.05),PSS decreased (6.72±4.55)% (P<0.01). Conclusions：There are two systems in the portal system, namely, gastrosplenic (GS) system and portomesenteric (PM) system, and between the two systems there is a functional barrier. DSRS+SPD+Disconnection operation can strengthen this barrier.