Abstract:Objective：To compare the effect, advantages and disadvantages of single-layer eversion choledochojejunostomy and posterior wall single-layer inversion and anterior wall single-layer eversion choledochojejunostomy. Methods：Patients who undergoing choledochojejunostomy were randomly divided into 2 groups:observation group, 95 cases, had single-layer eversion choledochojejunostomy; Control group, 92 cases, had posterior wall single-layer inversion and anterior wall single-layer eversion choledochojejunotomy. The anastomotic stoma size, time to perform the anastomosis, post-operative complications and outcome of the 2 types of operation were compared and analyzed. Results：The time to perform the anastomosis and the post-operative outcome of the observation group were better than those of the control group(P<0.05), but post-operative complications between the 2 groups were not statistically different. Conclusions：Single-layer eversion choledochojejunostomy is easy to perform, the operative time is short, and is a safe, reliable and rational anastomotic procedure.