影响分化型甲状腺癌预后的多因素分析
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Multifactorial analysis of prognosis of differentiated thyroid carcinoma
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    摘要:

    目的:探讨影响分化型甲状腺癌(DTC)预后的因素。
    方法:回顾性分析9年间治疗的DTC 患者429例的临床资料, 对其预后进行单因素和多因素分析。
    结果:全组 5,10年生存率分别为95.2% 和88.7%。单因素分析显示:患者年龄、肿瘤大小、T分期、远处转移、治疗方式、复发和临床病理分期等为影响预后的因素(P<0.05);而性别、病理类型、淋巴结转移等因素的组间差异均无显著性(P>0.05)。Cox多因素分析表明,T分期、治疗方式和临床病理分期3个因素均有统计学意义(P<0.05)。
    结论:年龄、肿瘤大小、T分期、复发、远处转移和临床病理分期是影响分化型甲状腺癌预后的主要因素, 其中T分期、治疗方式和临床病理分期为独立的预后因素。

    Abstract:

    Abstract:Objective:To investigate the factors that influence the prognosis of differentiated thyroid carcinoma(DTC).
    Methods :Retrospective analysis the clinical data of 429 cases of DTC treated in our hospital in 9 years was done, and monoand multifactorial analyses related to the prognosis of DTC were performed.
    Results:The overall 5, 10year survival rates were 95.2% and 88.7% respectively. Monofactorial analysis showed that age, tumor size, T stage, distantmetastasis, treatment modallty, recurrence, and clinicopathologic stage were prognostic factors (P<0.05); gender, pathological type, and lymph node metastasis had no significantce (P>0.05). Cox multifactorial analysis showed that the T stage, treatment modality and clinicopathologic stage were independent prognostic factors of DTC(P<0.05).
    Conclusions:Age, tumor size, T stage, distantmetastasis, treatment modality, recurrence, and clinicopathologic stage were main prognostic factors, and T stage, treatment modality and clinicopathological stage were independent prognostic factors of DTC.

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陈勇军, 刘谨文, 张林, 李兴睿, 吴高松, 吴毅平, 吴亚群, 易继林.影响分化型甲状腺癌预后的多因素分析[J].中国普通外科杂志,2007,16(11):6-105.
DOI:10.7659/j. issn.1005-6947.2007.11.006

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  • 在线发布日期: 2007-11-25