甲状腺术后迟发性声音嘶哑临床分析
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郭仁宣

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Clinical analysis of delayedonset hoarseness after thyroidecomy
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    摘要:

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    目的 探讨甲状腺手术后迟发性声音嘶哑的发生原因及治疗措施。
    方法 对近10年间收治的3 180例甲状腺手术患者及术后发生迟发性声音嘶哑102例(3.2 %)的临床资料进行回顾性分析。
    结果 甲状腺癌术后迟发性声音嘶哑发生率为5.1%(20/398),明显高于良性病变的2.9%(82/2 791)(P<0.05);不保留后被膜,于包膜外甲状腺下动脉主干结扎发生迟发性声音嘶哑43例(4.8%),明显高于保留后被膜,在包膜内结扎甲状腺下动脉分支者(2.3 %)(P<0.05);再次手术者的发生率(6.5%)明显高于初次手术者(3.0%)(P<0.05)。显露和不显露喉返神经,迟发性声音嘶哑发生率分别为3.1 %和3.3 %,两者无明显差异(P>0.05)。超声检查发现声音嘶哑的患者均有不同程度的手术创腔内积液。77例发病后给予综合治疗,治愈75例(97.4 %),恢复率明显高于未治疗者(84.0 %)(P<0.05)。
    结论 手术中减少组织损伤,减轻组织炎症水肿及术后创腔充分引流,可预防甲状腺手术后迟发性声音嘶哑发生。采取积极有效的综合治疗是治愈这一并发症的关键。

    Abstract:

    Abstract:Objective To investigate the cause and treatment of delayedonsef hoarseness after thyroidecomy.
    Methods The clinical data of 3180 cases of thyroid disease treated by surgery in our department between 1995~2005 and the 102 cases(3.2%) who developed postoperative delayedonset hoarseness were analyzed respectively.
    Results The complication rate of postoperative delayedonset hoarseness for thyroid carcinoma was 5.1%, which was obviously higher than that of benign thyroid disease (2.9%)(P<0.05). The rate in patients in whom the inferior thyroid arteries were ligated intracapsularly and the posterior thyroid capsule was retained (2.3%) was significantly lower than that in patients with extracapsular ligation of the arteries and the posterior capsule was not retained (4.8%, P<0.05). The complication rate in reoperative patients (6.5%) was markedly higher than that in patients who underwent primary operation (3.0 %)(P<0.05). However, there was no difference between the cases in which the recurrent laryngeal nerves were exposed and those in which the nevers were not exposed(P>0.05). In all of the patients with delayedonset hoarseness, ultrasonographic exammation showed various degrees of fluid accumulation in the operative field. Seventyfive of 77 cases(97.4%) with this complication were cured with combined theropy, which was significantly higher than the recovery rate of those cases without treatment(84.0%)(P<0.05).
    Conclusions Adequate drainage plays an important role in preventing delayedonset hoarseness. Applying aggressive combined therapy is the key point to cure this complication.

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何忠野,葛春林,郭克建,郭仁宣.甲状腺术后迟发性声音嘶哑临床分析[J].中国普通外科杂志,2007,16(1):5-.
DOI:10.7659/j. issn.1005-6947.2007.01.005

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  • 收稿日期:2006-08-04
  • 最后修改日期:2006-10-23
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  • 在线发布日期: 2007-01-25