Abstract:Objective:To explore the clinical efficacy of laparoscopy-assisted radical D2 proximal gastrectomy. Methods :The clinical data of 22 cases of laparoscopy-assisted D2 radical proximal gastrectomy were analysed retrospectively. Results:Laparoscopy-assisted radical proximal gastrectomy was carried out in all of the 22 cases. There was no conversion to open surgery in this series. The mean operation time was 188(162~270) min. The mean operative blood loss was 182(100~260)mL. The number of lymph nodes dissected was 18.6(10~32). The average time for gastrointestinal function recovery was 78(48~140)h. Postoperative anastomotic leakage occurred in one patient who had tumor invasion of distal esophagus, and it healed after 4 weeks of conservative treatment. There were no postoperative deaths in this series. All the 22 cases were followed up for 1~37 months (mean 9.2 months) and revealed no recurrence or metastasis. Conclusions:Laparoscopy-assisted radical D2 proximal gastrectomy for early and advanced gastric cancer is feasible, safe, and minimally invasive.