Abstract:Objective To study the clinicopathologic features,diagnosis and treatment of pancreatic cystadenoma and cystadenocarcinoma. Methods A retrospective clinicopathologic analysis was made on 17 cases of pancreatic cystadenoma and cystadenocarcinoma admitted from June 1996 to March 2007. Results Pancreatic cystic neoplasms had no specific clinical features. Ultrasonography and CT can be used to discover tumor ,but they can not be used for tumor differentiation.Tumor enucleation was performed in 7 cases of serous cystadenomas; for 6 cases of mucinous cystadenoma,pancreaticoduodenectomy was performed in 1 case,and resection of body and tail resection of pancreas in 5 cases. Four cases of cystadenocarcinoma were treated by pancreaticoduodenectomy plus lymphadenectomy in 1 case,resection of body and tail of pancreas in 2 cases, and resection of body and tail of pancreas plus splenectomy in 1 case. Fifteen cases were followed up with a median period of 42(1-129) months and without tumor recurrence.One elderly patient with cystadenocarcinoma who underwent resection of body and tail of pancreas plus splenectomy died 6 months after operation. Others had survived and without tumor recurrence on ultrasound exam, but one had diabetes mellitus. Conclusions Ultrasonography and CT scan are helpul in the diagnosis of pancreatic cystic neoplasms. Increase in the knowledge of the clinicopathologic features of this disease is the key to improve the level of diagnosis and treatment.Surgical resection gives good therapeutic results.