Observations on therapeutic outcome of operation combined with hyperthermic intraperitoneal lavage chemotherapy in treatment of stages Ⅲb and IV gastric cancer
Abstract:Objective:To discuss the effect of intra-operative and post-operative hyperthermic intraperitoneal lavage chemotherapy for Ⅲb and IV gastric cancer on post-operative peritoneal metastasis and survival rate. Methods :The clinical data of 31 cases of gastric cancer (control group) who underwent operation only and 50 cases (chemotherapy group) who receved operation combined with intra-operative and post-operative hyperthermic intra-peritoneal lavage chemotherapy were comparatively studied. Results:The survival rate of control group after 2 years and 3 years was lower than that of the chemotherapy group, and the intraperitoneal recurrence rate of control group after 2 years and 3 years was higher than that of chemotherapy group. Conclusions: Intra-operative and post-operative hyperthermic intraperitoneal lavage chemotherapy for gastric cancer has important significance in prevention and treatment of peritoneal metastasis and can improve survival rate.