手术联合腹腔温热灌注化疗治疗Ⅲb,Ⅳ期胃癌的疗效观察
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王生祥

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Observations on therapeutic outcome of operation combined with hyperthermic intraperitoneal lavage chemotherapy in treatment of stages Ⅲb and IV gastric cancer
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    摘要:

    目的:探讨Ⅲb,Ⅳ胃癌术中、术后腹腔温热灌注化疗对其术后腹膜转移和生存率的影响。
    方法:对比研究胃癌单纯手术(对照组,31例)和手术加术中、术后腹腔温热灌注化疗(化疗组,50例)的临床资料。结果:化疗组2年及3年生存率高于对照组,腹腔2年及3年复发率低于对照组。
    结论:胃癌术中、术后腹腔温热灌注化疗对防治肿瘤腹膜转移,提高生存率有重要意义。

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    Abstract:Objective:To discuss the effect of intra-operative and post-operative hyperthermic intraperitoneal lavage chemotherapy for Ⅲb and IV gastric cancer on post-operative peritoneal metastasis and survival rate.
    Methods :The clinical data of 31 cases of gastric cancer (control group) who underwent operation only and 50 cases (chemotherapy group) who receved operation combined with intra-operative and post-operative hyperthermic intra-peritoneal lavage chemotherapy were comparatively studied.
    Results:The survival rate of control group after 2 years and 3 years was lower than that of the chemotherapy group, and the intraperitoneal recurrence rate of control group after 2 years and 3 years was higher than that of chemotherapy group.
    Conclusions: Intra-operative and post-operative hyperthermic intraperitoneal lavage chemotherapy for gastric cancer has important significance in prevention and treatment of peritoneal metastasis and can improve survival rate.

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王生祥, 陈红兵 , 陈文元, 王吉胜, 苏发德, 田海萍.手术联合腹腔温热灌注化疗治疗Ⅲb,Ⅳ期胃癌的疗效观察[J].中国普通外科杂志,2007,16(4):2-.
DOI:10.7659/j. issn.1005-6947.2007.04.002

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  • 在线发布日期: 2007-04-25