Abstract:Objective:To study the value of surgical treatment for hepatocellular carcinoma (HCC) with tumor thrombi in vascular system.
Methods :The clinical data of 68 patients of HCC with tumor thromb in the vascular system who underwent hepatic resection with tumor thrombectomy, from Jan 1993 to Jan 2001, were retrospectively analyzed. Among them, 63 patients had tumor thrombus of portal vein, 1 patient had tumor thrombus of left hepatic vein, 1 patient had tumor thrombus of middle hepatic vein and left branch of portal vein, 1 patient had tumor thrombus of right hepatic vein, inferior vena cava and right branch of portal vein, and 2 patients had tumor thrombus of inferior vena cava. Six patients with tumor thrombus of portal vein caused by HCC underwent portal vein chemotherapy (PVC) after operation.
Results:Six patients died from liver and kidney function failure 3 months after operation; 62 patients made a good recovery. The 1-, 3- and 5-year survival rate was 41.7%, 20.8% and 4.1%, respectively.
Conclusions:Hepatic resection with tumor thrombectomy is effective in treatment of HCC with tumor thrombi in vascular system. After operation, adjuvant treatment can have a favourable effect on the prognosis.