Abstract:Objective:To explore a method to improve the radical resection and survival rate of hilar cholangiocarcinoma.
Methods :Fifty-eight consecutive patients with hilar cholangiocareinoma who underwent anatomic hepatectomy together with caudate lobectomy from Feb 1998 to June 2006 were studied retrospectively.
Results:Tumor resection combined with anatomic left hemihepatectomy was performed in 26 patients, combined with anatomic right hemihepatectomy in 25 patients, with right hepatic trisectionectomy in 4 patients, and with middle hepatectomy in 3 patients. The entire caudate lobe was resected and skeletization lymph node dissection of the hepatoduodenal ligament was performed in all cases. The radical resection rate was 72.4 ％(42/58), and the 1-,and 3-year survival rate was 79.5 ％, and 36.2 ％ respectively. At present, 3 cases have tumor-free survival for 6-year.
Conclusions:Tumor resetion combined with anatomic hepatectomy and caudate lobectomy can offer a better chance of long-term survival in some selected patients with advanced hilar cholangiocarcinoma. Skilled surgical technique can result in better outcomes.