Abstract:Objective:To explore the clinical value of B ultrasound-guided psychro-circulation percutaneous microwave coagulation therapy(PMCT) in the treatment of liver cancer.
Methods :One hundred and sixteen liver cancer patients with 154 lesions were selected to receive psychro-circulation PMCT in our department from July 2004 to December 2007. The pre-and postoperative alpha fetoprotein(AFP) levels were detected. The diameters and blood flow state of the tumors were measured and compared by use of B ultrasound and computerized tomographic scanning(CT).The postoperative 1,2 and 3 y survival rate of those patients was followed up and recorded.
Results:No mortality or severe complications occurred in this series.Preoperative serum AFP level of the patients was (421.6±36.5)μg/L and decreased obviously to （232.5±25.6）μg/L at 1 month after psychro-circulation PMCT（P<0.01）.Preoperative tumor diameter was (48.6±10.2) mm and diminished to (37.5±7.8) mm at 1 month postoperatively（P<0.05）.At 3 months postoperatively,the liver tumors disappeared completely in 15 cases, obviously decreased in size in 86 cases and no marked changes occurred in 15 cases. In the patients with primary hepatic carcinoma,the postoperative 1,2 and 3 y survival rate was 89.4%,67.1%, and 43.8%,respectively. In the patients with secondary hepatic carcinoma,the postoperative 1,2 and 3 y survival rate was 82.1%,53.8%, and 24.0%,respectively.
Conclusions:Psychro-circulation PMCT is an effective method for treating liver cancer and is especially suitable for inoperable patients, because of its mini-trauma,few complications and convenient performance.