Background and Aims Intraabdominal infections are common complications in patients after partial hepatectomy for hepatolithiasis, which will increase patient pain and treatment costs, prolong hospital stays, and even cause life-threatening infectious shock. This study was performed to determine the risk factors for the occurrence of intraabdominal infections after partial hepatectomy in such patients through a retrospective analysis, so as to provide a basis for the prevention of postoperative intraabdominal infections.Methods The clinical data of 54 patients with hepatolithiasis undergoing partial hepatectomy in the Hospital of the Marine Corps of PLA from March 2017 to February 2021 were retrospectively analyzed. A univariate analysis was performed on the factors that may affect the occurrence of postoperative intraabdominal infections, and then the factors with statistical significance were further identified by multivariate Logistic regression analysis.Results Of the 54 patients, postoperative intraabdominal infections occurred in 8 cases (14.8%), and none of them required a re-operation, and all were cured. Univariate analysis showed that the age ≥60 years (χ²=7.091, P=0.008), the preoperative serum albumin (ALB) level <35 g/L (χ²=7.858, P=0.005), and the fluid volume of the surgical field flush <2 L (χ²=6.291, P=0.012) were associated with the occurrence of postoperative intraabdominal infections; further Logistic regression analysis revealed that the advanced age (P=0.025), low preoperative ALB level (P=0.044), and low fluid volume of the surgical field flush (P=0.019) were independent risk factors for the development of postoperative intraabdominal infections.Conclusion The incidence of intraabdominal infections is relatively high after partial hepatectomy for hepatolithiasis. The advanced age (≥ 60 years), low preoperative ALB level (<35 g/L) and insufficient the amount of the surgical field flush (<2 L) are the independent risk factors for the occurrence of postoperative intraabdominal infections. Thus, improving the preoperative ALB level and adequate intraoperative surgical field flush are helpful for preventing the occurrence of intraabdominal infections.