Photodynamic therapy (PDT) is an effective minimally invasive treatment for tumors, which can be combined with other systemic treatments such as biliary stenting, extrahepatic bile duct drainage, and chemotherapy for the treatment of cholangiocarcinoma. It is mainly suitable for the treatment of unresectable cholangiocarcinoma and adjuvant therapy for postoperative residual or local recurrence of tumors, which can effectively control local tumor progression, relieve biliary obstruction, improve patients' quality of life, prolong survival, and has the advantages of being minimally invasive, precise and repeatable. Currently, there is limited clinical evidence for the use of PDT in cholangiocarcinoma, and there is a lack of clinical technical standards and consensus. The Group of Operative Surgery, Branch of Surgery, Chinese Medical Association, Group of Biliary Surgery, Branch of Surgery, Chinese Medical Association and Chinese Committee of Biliary Surgeons organized relevant experts to discuss the indications, contraindications, technical operation standards, efficacy evaluation, and complications management of PDT, and reached a consensus, aiming to provide a reference for the clinical application of PDT in the treatment of cholangiocarcinoma.