腹膜粘连无创评估手段的进展
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作者单位:

1.广东医科大学 第一临床医学院,广东 湛江 524000;2.广州市第一人民医院/华南理工大学附属第二医院 结直肠肛门外科,广东 广州 510030

作者简介:

欧阳子祺,广东医科大学第一临床医学院硕士研究生,主要从事外科疾病与并发症方面的研究。

基金项目:

国家自然科学基金资助项目(81900493);广东省广州市科学技术局基础与应用基础研究基金资助项目(202102020836)。


Advances in non-invasive assessment methods for peritoneal adhesions
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Affiliation:

1.Guangdong Medical University First School of Clinical Medicine, Zhanjiang, Guangdong 524000, China;2.Department of Colorectal and Anal Surgery Guangzhou First People's Hospital/the Second Affiliated Hospital of South China University of Technology, Guangzhou 510030, China

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    摘要:

    腹膜粘连是指手术、创伤、腹腔感染、腹膜透析等病因导致的腹腔脏器和组织修复过程中形成的异常的纤维连接。腹部手术是腹膜粘连的最常见原因,绝大多数腹部手术患者术后均会出现不同程度的腹膜粘连。腹膜粘连可以导致患者出现长期的腹痛、诱发肠梗阻,部分患者可能因为粘连带的卡压而出现急性肠坏死。而在女性中,腹膜粘连增加了女性不孕的风险。除此之外,腹膜粘连可以使二次手术变得困难,术中容易出现副损伤。通过无创手段来评估腹膜粘连的程度,筛查腹膜粘连的高危人群,评估药物和屏障材料的临床效果,具有重要的临床意义。超声检查、磁共振电影成像和人工气腹CT能够对腹膜粘连进行精准评估。除此之外,体质量指数、炎症标志物以及赖氨酰氧化酶样蛋白2等指标也对粘连的评估有一定的价值。笔者对目前的腹膜粘连无创评估手段进行综述,以期为临床提供参考。

    Abstract:

    Peritoneal adhesions refer to abnormal fibrous connections that form during the repair process of abdominal organs and tissues due to various causes such as surgery, trauma, intra-abdominal infections, and peritoneal dialysis. Abdominal surgery is the most common cause of peritoneal adhesions, and the majority of patients who undergo abdominal surgery will experience varying degrees of peritoneal adhesions after surgery. Peritoneal adhesions can lead to long-term abdominal pain, induce intestinal obstruction, and in some cases, acute intestinal necrosis due to constriction by adhesions. In females, peritoneal adhesions increase the risk of infertility. Furthermore, peritoneal adhesions can make subsequent surgery difficult, with a higher risk of associated injuries. Non-invasive methods for assessing the extent of peritoneal adhesions, screening high-risk populations for adhesions, and evaluating the clinical effectiveness of drugs and barrier materials are of significant clinical importance. Ultrasonography, cine magnetic resonance imaging, and artificial pneumoperitoneum CT can provide precise assessments of peritoneal adhesions. In addition, parameters such as body mass index, inflammatory markers, and lysyl oxidase-like protein 2 also have some value in evaluating adhesions. In this review, the authors summarize the current non-invasive assessment methods for peritoneal adhesions, aiming to provide clinical insights and guidance.

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欧阳子祺,李冠炜.腹膜粘连无创评估手段的进展[J].中国普通外科杂志,2023,32(9):1410-1414.
DOI:10.7659/j. issn.1005-6947.2023.09.015

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  • 收稿日期:2023-03-24
  • 最后修改日期:2023-05-20
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  • 在线发布日期: 2023-11-03