The American College of Gastroenterology Guidelines: Management of Acute Pancreatitis (referred to as the "2024 guidelines"), released in March 2024, presents 11 recommendations and 23 key concepts for the management of acute pancreatitis (AP) based on different levels of evidence quality. The 2024 guidelines provide detailed explanations regarding the diagnostic criteria, etiology, initial assessment, severity stratification, initial management, endoscopic retrograde cholangiopancreatography, antibiotic use, nutritional support, and surgical interventions for AP. Compared to the 2023 edition of the American College of Gastroenterology Guidelines, the 2024 edition offers more detailed recommendations and comprehensive evidence-based medical data, which is of great significance in optimizing the diagnosis and treatment process for AP patients and improving patient outcomes.